Tags pharmaceuticalsSTAT+ STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. GET STARTED Ed Silverman And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, as you know, our treasured signal to daydream about weekend plans. Our agenda includes another installment in the “Let’s-see-them-before-they-die” concert series, but otherwise, we plan to catch up on reading and take a few naps. And what about you? This could be an opportunity to connect with someone special or take stock of the world, such as it is. Or you could simply tune everything out and curl up with a good e-book. Well, whatever you do, have a grand time, but be safe. Enjoy, and see you soon …GlaxoSmithKline investors want the pay package slashed for the new chief executive, Emma Walmsley, because it is not sufficiently lower than what was given her predecessor, Andrew Witty, SkyNews reports. Witty was paid about $1.3 million in base salary and received roughly $8 million in total compensation. Some Glaxo shareholders say her pay should appropriately reflect her experience as head of the consumer products business. Pharmalot, Pharmalittle: Glaxo investors angry over pay package for new CEO What’s included? Alex Hogan/STAT About the Author Reprints By Ed Silverman March 3, 2017 Reprints Pharmalot Log In | Learn More What is it? Pharmalot Columnist, Senior Writer Ed covers the pharmaceutical industry. [email protected] @Pharmalot Unlock this article — plus daily coverage and analysis of the pharma industry — by subscribing to STAT+. First 30 days free. GET STARTED Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.
CARY, N.C. – Kirk Triplett holed out from 143 yards for eagle on the par-4 18th hole Saturday to take a two-stroke lead in the Champions Tour’s SAS Championship. Triplett, the ACE Group Classic winner in February for his third victory on the 50-and-over tour, finished with a bogey-free 9-under 63 to reach 11-under 133 at rain-softened Prestonwood. ”I think the conditions were a little different from yesterday, a little softer, so personally, I felt you could be a little more aggressive,” Triplett said. ”Some of the holes played pretty short yesterday, a little bit longer today. I think the course was similar to how it played the last two years, so I think in some ways, it was more familiar to me.” Paul Goydos and Tom Lehman were tied for second. Goydos, the Hawaii Championship winner last month for his first senior title, had a 67. Lehman shot 68. Goydos flew his tee shot in the water and bogeyed the first hole of the day. He called his opening shot a ”bit of a wake-up call.” ”I just kind of hung in there and made a couple of nice birdies on 6 and 7,” Goydos said. ”But I’ve got a feeling tomorrow you’re going to have to go low and make a lot of birdies.” First-round leader Guy Boros was tied for fourth at 11 under, following a 66 with a 70. Boros is making his second tour start after turning 50 last month. Fred Funk also was 11 under after a 64. Boros faltered with bogeys on 14 and 15, while Funk birdied five of the last eight holes. Funk said he was having issues with his calf Friday, but he felt better for the second round. ”I was struggling to even hit the golf ball (Friday),” Funk said. ”Today, I was feeling a lot better and was able to swing at it, so I picked up about 30 yards on my drive.” Bernhard Langer, the 2012 winner, was tied for ninth at 6 under after a 65. Langer has a tour-high five victories – two of them majors – and leads the money list and Charles Schwab Cup points race. Montgomerie, second in the Schwab Cup standings, was another stroke back after a 66. He has two major victories this year. Defending champion Russ Cochran was 4 under after a 69.
A woman has been awarded £30,000 from her father’s estate despite the fact that he made it clear he had disinherited his children, in the first judgment of its kind since a landmark Supreme Court ruling that was thought to clarify testamentary freedom and what constitutes reasonable provision.Elena Nahajec was awarded the figure from Stanley Nahajec’s £240,000 estate under the Inheritance (Provision for Family and Dependants) Act 1975.In the judgment, handed down at the County Court at Leeds, His Honour Judge Saffman said Nahajec should be due maintenance because she wanted to complete a veterinary course.The award was despite her having almost no contact with her father for several years before his death 2015. He left a letter explicitly disinheriting all three of his children, instead leaving the whole of his estate to his friend Stephen Fowle.Mark Nahajec, a half-sibling of Elena who was unable to work through ill-health, made a claim under the 1975 act which was settled for £22,000. The third sibling, Philip Nahajec, made no claim.Like the Supreme Court’s ruling in Ilott v The Blue Cross and Ors earlier this year, the case centred on reasonable financial provision. Julia Burns, associate in the wills, trusts and estates disputes team at Irwin Mitchell Private Wealth, said that after Ilott it was thought that estrangement could be fatal or severely reduce the value of an award.‘The award was 11.3% of the estate which is very similar to that in the Ilott case (within 1%). There was specific mention of her wanting to do a veterinary course so this is an example of something that falls under the definition of “maintenance” post Ilott. This means that estranged child claims are not dead in the water but suggests that any claimants will need to show a track record of reconciliation attempts in order for the Judges to consider their views.’Saffman wrote: ‘£30,000 is my best estimate of the capitalised cost of maintenance for a reasonable time going forward to take into account the possibility, albeit contingent, of the claimant undertaking a course which ultimately results in her becoming a veterinary nurse.’
There was a great party atmosphere in the B&S Credit Union yesterday for the first members’ draw of 2019. The highly-anticipated event had amazing prizes up for grabs, including cash prizes totalling €9500, spot prizes and a brand new 191 Ford Fiesta.Ballybofey local Patrick O’Brien was the lucky winner of the top prize, winning himself a stylish new car from Shane Connolly Cars. B&S Credit Union car draw winner Patrick O’Brien is interviewed by Paddy McMenaminB&S Credit Union car draw winner Patrick O’Brien is presented with the keys to his new 191 Ford FiestaPatrick O’Brien tests out his brand new 191 Ford FiestaA large gathering of credit union staff, MC Paddy McMenamin and members were there to celebrate the big reveal as a delighted Patrick was handed the keys to his new motor.Other top winners in the draw were Joe Blee from Ballybofey, who won a fantastic €2,000 cash prize.Five lucky winners bagged €1,000 prizes, including Rose Callaghan from Stranorlar, Breege Kelly from Ballybofey, Bridgeen McGlynn from Cloghan, Rita Bryson from Castlefinn and Amy McElchar from Ballybofey.Bernadette Kelly and Caroline Gillespie from Ballybofey both won €750, while Denise Tourish and Lynne Smyth from Castlefinn picked up a cool €500 each. B&S Credit Union car draw, 12th February 2019B&S Credit Union car draw, 12th February 2019B&S Credit Union car draw, 12th February 2019B&S Credit Union car draw, 12th February 2019The hugely successful draw means many happy credit union members will be starting 2019 off with a financial boost.And the good news is that there is a SECOND car draw taking place in just six months’ time!www.bandscu.ieLucky Patrick wins a new car in B&S Credit Union draw! – Picture Special was last modified: February 13th, 2019 by Staff WriterShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:191 Ford FiestaB&S credit unioncar draw
Tags:#Amazon#BNSF Railroad#CNN#drone regulation#drones#FAA#Michael Drobac#PrecisionHawk#uav Top Reasons to Go With Managed WordPress Hosting richard procter Related Posts Why Tech Companies Need Simpler Terms of Servic… 8 Best WordPress Hosting Solutions on the Market A Web Developer’s New Best Friend is the AI Wai… Little by little, the FAA seems to be unclenching from its strict regulatory limits on commercial-drone use.Earlier this week, the agency said it would allow three companies to push past the boundaries of restrictive drone guidelines the FAA proposed earlier this year. Specifically, the FAA will allow these companies to test commercial drones that operate beyond their operator’s direct vision and, in one case, in urban areas.Would-be commercial drone operators—particularly Amazon and its proposed Prime Air delivery service—have long chafed at the FAA’s unwillingness to allow broader testing and use of remotely piloted copters. The FAA’s proposed rules, for instance, would force all commercial-drone operators to obtain FAA certification, limit flights to daylight hours and altitudes of less than 500 feet, and require drones to remain within their operators’ lines of sight.See also: The FAA Finally Suggests Drone-Use Rules—And They Don’t Allow MuchNow, however, the FAA says it will allow PrecisionHawk, a North Carolina-based remote sensing and data processing company, to use drones to survey crops in rural areas beyond visual range of their operators. BNSF Railroad, meanwhile, will do something with drone inspections of its rail infrastructure, again outside operator line-of-sight. In a separate effort, CNN will explore using drones for news gathering in populated urban areas.“Even as we pursue our current rulemaking effort for small unmanned aircraft, we must continue to actively look for ways to expand non-recreational [unmanned aircraft systems] uses,” FAA administrator Michael Huerta said at the Association for Unmanned Vehicle Systems International Unmanned Systems 2015 conference this week. “This new initiative involving three leading U.S. companies will help us anticipate and address the needs of the evolving UAS industry.”Drone enthusiasts find the FAA’s move heartening.“It’s a very big development,” Michael Drobac, executive director of the Small UAV Coalition, said in an interview with ReadWrite. “Based on what they had been saying, the future of commercial drone use and even continued excitement around consumer drone use looked somewhat bleak. This represents a significant pivot on their part.” Photo by John Mills
Upgrade to a 10 GbE network connection cuts the execution time in half once more. Upgrade to SSD hard-drives & caching software gives you another 80 percent speed improvement, and Girish Juneja is CTO of Datacenter Software Division and General Manager of the Big data and Expressway software businesses. Girish has over 21 year experience in building software businesses, at Intel, as an entrepreneur and earlier at Verizon Telecommunications. Prior to his current position, he was the Director of Application Security & Identity Products in the Software Services Division in SSG. In this role he was responsible for conceptualization, product development, sales & marketing of Intel Expressway software product line for Service Providers, ISVs, OEMs and select end-users. Girish also led the development of Identity software strategy for SSG that led to acquisition of Nordic Edge, development & launch of McAfee Identity Manager & Intel CloudSSO Identity-as-a-Service offering in collaboration with Salesforce.com. Girish joined Intel in 2005 with the acquisition of Sarvega, a company he founded. Girish received his MBA from University of Chicago, MS Computer Science from University of Maryland, and a Bachelor’s degree in Electrical & Electronics Engineering from BITS, Pilani, India.IntroductionThe amount of data that companies need to process is growing increasingly larger and the problem of Big Data is only going to get bigger as more organizations realize the benefits of working through enormous data sets in real time.In fact, the Big Data market was estimated to be $5 billion for 2012 and is predicted to reach $53 billion by 2017, according to Wikibon Market Research. About 2.8 zettabytes of data were generated worldwide in 2012 and the amount will increase to 40 zettabytes in 2020, according to the IDC Digital Universe report.Whether you need to quickly analyze consumer behavior, sort through personal location data from millions of smartphones, or detect credit card fraud as it is happening, Big Data generates significant financial value across a myriad of sectors. Many organizations are turning to the open source Hadoop framework for churning through vast sets of unstructured data. However, their efforts to go beyond pilot phase of testing the technology for use are hampered by several issues, including immature elements of non-functional aspects of Hadoop deployment, security & management, availability of experienced Hadoop specialists, optimized deployment of hadoop framework on current and evolving compute, storage, virtualization & network infrastructures to deliver optimal performance & lower query latencies and lack of easy and seamless integration of Hadoop based “data lakes” with other deployed Enterprise software such as Data warehouses, business intelligence & in-memory databases.This is why we created the Intel® Distribution for Apache Hadoop* (IDH), and the support/services capabilities around it worldwide and are investing resources into the community directly to expand the capabilities of Apache Hadoop into handling data explosion related data center software.Hadoop continues to evolve rapidly and being open source, can be downloaded by everyone easily, without costs & used to evaluate its ability to address diverse set of big data problems including data warehouse like reporting queries, text searches over vast data sets, low latency near real time querying etc., as the framework gets improved with help of several companies such as Intel and others investing aggressively to improve the framework in open source.Enterprise Grade Management and ReliabilityIntel has over 3 years of experience extending, building, deploying & optimizing Hadoop framework with some of our largest cloud, telecommunications & enterprise partners. This experience, combined with output of research from Intel Labs in optimizing Hadoop clusters through innovations in machine learning, has provided us some unique perspectives on how to provide enterprise grade manageability missing from the framework.The Intel Manager in IDH includes wizards that will efficiently guide you through tasks and workflows, while tabbed navigation helps you quickly navigate between components. It simplifies deployment of HDFS and HBase, HIVE and the rest of the Hadoop platform.In addition, we have established worldwide enterprise-grade support and services backed by Intel & its ISV & OEM partners.Ready for Production: Security & PerformanceScores of Intel engineers are working on Project Rhino, a completely open source effort to create a security framework in Apache Hadoop that has been missing since its genesis. The intent is to improve Apache Hadoop so it has a common security framework, including a common authorization framework, single-sign on, authentication, enhanced audit logging and data confidentiality.As an example, several recent news events related to data leaks have raised the awareness that data confidentiality is an absolute must have for production deployment of Apache Hadoop based “data lake” environment.However, both HDFS and HBase today do not have encryption built into their architecture. Intel has already extended the compression codec to enable encryption, validated and tested HDFS encryption and decryption on petabyte scale data, enabled acceleration of encryption through Intel AES-NI instruction set that reduces the cost of encryption to near-zero, and provided management controls using Intel Manager and its APIs to configure encryption and keystores. This has been contributed to the open source Hadoop community as well in order to make these innovations available to all distributions.We have designed the Intel Manager Administration Console, as well as our entire IDH distribution, to seamlessly integrate with Kerberos, LDAP and Active Directory protocols. Even more importantly, we have done this in a holistic way, considering the entire Apache Hadoop ecosystem, as well as the entire organizational security picture. This provides a single point of entry for your administrators managing the Hadoop clusters and your developers looking for their job logs and other job stats. You can rest assured that all security features developed for IDH will integrate seamlessly with your other systems and will not be a band aid solution or a silo.The other main area where IDH differentiates itself is in performance. Leveraging Intel’s strength in optimizing software for hardware capabilities, we have tuned IDH to get maximum scalability and performance, especially when running on Xeon servers. IDH runs on all hardware platforms supported by Apache Hadoop, yet when combined with particular CPU, disk and network equipment it detects the enhanced capabilities of that hardware and automatically leverages those features if present. Under this configuration with the Intel® Distribution for Apache Hadoop* (IDH), the time to process this TeraSort benchmark plummets from more than four hours to less than 10 minutes.Intel Manager and IDH are tested & qualified to be rock solid when configuring, deploying and managing clusters, regardless of their size. Whether you are working on a one node POC cluster or a 1000 node production environment, you can rest assured that IDH will meet your needs.Girish For example, you can reduce processing time dramatically with our Big Data solution. Using a Xeon 5600 HDD with a 1 GbE connection to do a 1 TB TeraSort benchmark test will take more than four hours, but when you: Upgrade the processor to the latest chipsets, you reduce the required processing time by 50 percent
About the authorPaul VegasShare the loveHave your say Club Brugge hero Emmanuel Dennis: I wanted to show Real Madrid what they’d lostby Paul Vegas23 days agoSend to a friendShare the loveClub Brugge striker Emmanuel Dennis admits his goal celebration last night was a swipe at Real Madrid.The Nigerian struck twice in the 2-2 Champions League draw and followed up with a ‘Cristiano Ronaldo’ celebration.Afterwards, Dennis explained his actions: “I like Cristiano and for me he is the best player in the world. “I became sad when he left Madrid and celebrated my goals to show that they had lost something.”He added: “I am happy to have scored two goals, we really wanted to win the game and we were not far away, so we have to settle for a point, which is already a good result.”
Instagram/jwillpart2Jonathan Williams may not suit up for the Razorbacks again, but the Arkansas great should be ready to go when the NFL Draft process begins in earnest. Today, Williams got on the treadmill and ran for the first time since suffering a foot injury that cost him his senior season.On Sunday, Williams receiver a Senior Bowl invitation, despite missing this year. Things are definitely looking up for him.
When we put together the bracket for the 64 Most Annoying People In Sports Media a few weeks back, we were pretty sure we knew which two personalities would be facing off in the championship game. Now that we’re here, we have no clue which of them is going to prevail.Stephen A. Smith and Skip Bayless, the two stars of ESPN’s First Take, have reached the final. Neither was even realistically challenged along the way.This past week, 1-seed Smith knocked off 11-seed Jemele Hill, while 1-seed Bayless handled 16-seed Jim Rome in the Final Four. Both runs were impressive, but like all good things – they had to come to an end.Voting is now closed on the Final Four. You can view results from the first round here, the second round here, the Sweet 16 here, the Elite Eight here and the Final Four here. Let’s vote on the all-First Take final below.The 64 Most Annoying People In Sports Media: Championship GameVote On The Championship Game Here1. Stephen A. Smith vs. 1. Skip BaylessYou’ve all been waiting for this moment. Use your vote wisely. More Annoying: Stephen A. Smith or Skip Bayless?More: 10 Schools We Think Will Switch Conferences >>>
OTTAWA – Canada’s housing market rebound appears to be slowing amid diminishing increases in national home sales, says the Canadian Real Estate Association.The organization said on Monday that home sales saw their fourth consecutive increase in August, rising 0.9 per cent month-over-month to 39,366 from 39,028 and coming as roughly half of all local markets saw a month-over-month uptick.However, August home sales simultaneously experienced a 3.8 per cent non-seasonally-adjusted year-over-year drop.CREA attributed the drop to “major declines” in British Columbia real estate and stricter mortgage regulations that came into effect at the start of the year.“Improving national home sales activity in recent months continues to obscure significant differences in regional trends for home sales and prices,” said Gregory Klump, CREA’s chief economist. “Moreover, recent monthly sales increases are diminishing, which suggests the recent rebound may be starting to lose steam.”Economists said the slowdown signals a shift away from the “wild swings” the real estate market saw in recent years as prices and demand for homes skyrocketed, often causing a frenzied pace for sales.TD Economics economist Rishi Sondhi said, “While one month of data hardly makes a trend, August’s performance could be a sign that the worst is over for the province.Meanwhile, BMO Capital Markets chief economist Douglas Porter called the housing market “a bit of a yawner, neither drastically hot nor desperately cold” in his note to investors.“The outward calm masks some still-serious regional shifts beneath the placid surface,” he said, noting that measures aimed at cooling the B.C. market have resulted in some of the biggest sales declines in the country.The Greater Vancouver Area saw a 36.7 per cent year-over-year non-seasonally-adjusted decrease in sales activity, while Fraser Valley and Victoria saw 39.5 per cent and 17.6 per cent drops respectively, according to CREA.The Greater Toronto Area was faring better and continuing to stabilize, Porter said.GTA home sales rose 7.6 per cent year-over-year to 6,839 in August from 6,357 the year before. The region also saw a 2.2 per cent increase in homes sold month-over-month.“Toronto is very close to having a ‘normal’ market at this point,” said Porter. “Policymakers could not have asked for a better outcome, achieving the proverbial soft landing — at least so far.”The conditions caused CREA to forecast that 462,900 homes will be sold in the country this year, a 9.8 per cent drop from last year’s forecast of 513,280 homes. Looking ahead to 2019, CREA said it expects to see 472,700 homes change hands.CREA also noted that between July and August the number of newly-listed homes was unchanged, hovering around 69,000.It said the slight uptick in sales and the lack of new home listings pushed the Multiple Listing Service home price index up 2.5 per cent year-over-year.The disparity between the two numbers also caused the sales-to-new listings ratio to increase to 56.6 per cent in August from 56.2 per cent the month before.